Vital Essentials Bully Sticks Dog Treats are packed with essential nutrients and made with only fresh, whole USDA beef for the wholesome nutrition dogs instinctively crave. These healthy treats contain no added hormones or antibiotics and are completely free of grains, fillers, preservatives, coloring and rendered by-products. A slow, 48 hour freeze-drying process locks in nutrients without cooking the raw meat and allows these treats to be safely and conveniently stored without refrigeration.